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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TWF1
All Species:
33.94
Human Site:
S142
Identified Species:
67.88
UniProt:
Q12792
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12792
NP_002813.2
350
40283
S142
K
K
Y
L
L
S
Q
S
S
P
A
P
L
T
A
Chimpanzee
Pan troglodytes
XP_001165727
384
43939
S176
K
K
Y
L
L
S
Q
S
S
P
A
P
L
T
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543726
350
40067
S142
K
K
Y
L
L
S
Q
S
S
P
A
P
L
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91YR1
350
40061
S142
K
K
Y
L
L
S
Q
S
S
P
A
P
L
T
A
Rat
Rattus norvegicus
Q5RJR2
350
40072
S142
R
K
Y
L
L
S
Q
S
S
P
A
P
L
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508452
357
40765
S149
R
K
Y
L
L
S
Q
S
S
P
A
P
L
T
A
Chicken
Gallus gallus
Q5ZM35
349
39817
S142
Q
K
H
V
S
S
C
S
A
P
A
P
L
T
A
Frog
Xenopus laevis
Q68F50
350
40436
S142
Y
K
Y
L
A
C
Q
S
A
P
A
P
L
T
T
Zebra Danio
Brachydanio rerio
Q6GMH3
347
39840
S140
L
R
H
I
T
S
C
S
A
P
A
P
L
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFM9
343
39052
A142
R
R
H
K
Q
D
F
A
A
P
A
P
L
T
S
Honey Bee
Apis mellifera
XP_393653
350
39782
A143
H
K
Y
K
R
N
N
A
A
P
A
P
L
T
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53250
332
37052
T141
A
G
Q
N
K
P
L
T
H
D
E
E
M
Q
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.6
N.A.
97.7
N.A.
94.8
94.5
N.A.
89.9
66.8
79.7
63.1
N.A.
48.2
53.1
N.A.
N.A.
Protein Similarity:
100
90.6
N.A.
99.1
N.A.
97.7
97.4
N.A.
96.3
86.8
91.1
82.5
N.A.
72.2
74
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
93.3
N.A.
93.3
60
66.6
46.6
N.A.
33.3
46.6
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
86.6
73.3
73.3
N.A.
73.3
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
9
0
0
17
42
0
92
0
0
0
59
% A
% Cys:
0
0
0
0
0
9
17
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
9
0
25
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
34
75
0
17
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
59
50
0
9
0
0
0
0
0
92
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
9
0
9
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
0
0
92
0
92
0
0
0
% P
% Gln:
9
0
9
0
9
0
59
0
0
0
0
0
0
9
0
% Q
% Arg:
25
17
0
0
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
9
67
0
75
50
0
0
0
0
0
9
% S
% Thr:
0
0
0
0
9
0
0
9
0
0
0
0
0
92
17
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
67
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _